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Did you mean prasanna g l (10 results)?
Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration.
Crowley MA, Garland DL, Sellner H, Banks A, Fan L, Rejtar T, Buchanan N, Delgado O, Xu YY, Jose S, Adams CM, Mogi M, Wang K, Bigelow CE, Poor S, Anderson K, Jaffee BD, Prasanna G, Grosskreutz C, Fernandez-Godino R, Pierce EA, Dryja TP, Liao SM. Crowley MA, et al. Among authors: prasanna g. Hum Mol Genet. 2023 Jan 6;32(2):204-217. doi: 10.1093/hmg/ddac187. Hum Mol Genet. 2023. PMID: 35943778 Free PMC article.
Here, we assessed the role of alternative complement pathway component factor B (FB) in the formation of these deposits. RNA-seq analysis of the posterior eyecups revealed increased unfolded protein response, decreased mitochondrial function in the neural retina (by 3 mont …
Here, we assessed the role of alternative complement pathway component factor B (FB) in the formation of these deposits. RNA-seq anal …
Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells.
Zhang X, Krishnamoorthy RR, Prasanna G, Narayan S, Clark A, Yorio T. Zhang X, et al. Among authors: prasanna g. Exp Eye Res. 2003 Mar;76(3):261-72. doi: 10.1016/s0014-4835(02)00323-8. Exp Eye Res. 2003. PMID: 12573655
Western blot analysis of HNPE cells showed the expression of endothelin receptor A (ET(A)) and endothelin receptor B (ET(B)) with approximate molecular weights of 40 kDa. Dex treatment decreased ET(A) receptor expression at all Dex doses, but up-regulated ET(B …
Western blot analysis of HNPE cells showed the expression of endothelin receptor A (ET(A)) and endothelin receptor B (ET(B)) w …
Endothelin-1 and endothelin receptors in light-induced retinal degeneration.
Torbidoni V, Iribarne M, Ogawa L, Prasanna G, Suburo AM. Torbidoni V, et al. Among authors: prasanna g. Exp Eye Res. 2005 Sep;81(3):265-75. doi: 10.1016/j.exer.2004.12.024. Exp Eye Res. 2005. PMID: 16129094
We have studied the distribution of endothelinergic molecules: prepro-endothelin-1 (PPET-1), endothelin-1 (ET-1), and receptors A and B (ET-A) and (ET-B) in the retina of mice. The localization of these molecules in normal mice was compared to their localization in …
We have studied the distribution of endothelinergic molecules: prepro-endothelin-1 (PPET-1), endothelin-1 (ET-1), and receptors A and B …
Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
Lynch JM, Li B, Katoli P, Xiang C, Leehy B, Rangaswamy N, Saenz-Vash V, Wang YK, Lei H, Nicholson TB, Meredith E, Rice DS, Prasanna G, Chen A. Lynch JM, et al. Among authors: prasanna g. J Biol Chem. 2018 Dec 28;293(52):20137-20156. doi: 10.1074/jbc.RA118.004325. Epub 2018 Nov 2. J Biol Chem. 2018. PMID: 30389787 Free PMC article.
Synthesis of novel nitric oxide (NO)-releasing esters of timolol.
Chiroli V, Batugo MR, Biondi S, Bonfanti A, Brambilla S, Gale DC, Li L, Miglietta D, Nicoli F, Prasanna GA, Ronchetti D, Vernier WF, Chong WK. Chiroli V, et al. Among authors: prasanna ga. Bioorg Med Chem Lett. 2009 May 15;19(10):2785-8. doi: 10.1016/j.bmcl.2009.03.111. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19361986
Hindered esters A were designed and synthesized, whose 'triggered' release relied on enzymatic hydrolysis of the nitrate ester in A to B, that in turn cyclized to liberate timolol....
Hindered esters A were designed and synthesized, whose 'triggered' release relied on enzymatic hydrolysis of the nitrate ester in A to B …
Human optic nerve head astrocytes as a target for endothelin-1.
Prasanna G, Krishnamoorthy R, Clark AF, Wordinger RJ, Yorio T. Prasanna G, et al. Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2704-13. Invest Ophthalmol Vis Sci. 2002. PMID: 12147606
ET receptor involvement for cell proliferation was determined with BQ788 (an ETB antagonist), BQ610 (an ETA antagonist), PD142893 (an ET(A/B) mixed antagonist), and sarafotoxin 6C (S6C; an ET(B) agonist). ...The hONAs expressed mRNA for ET(A) and ET(B) recept …
ET receptor involvement for cell proliferation was determined with BQ788 (an ETB antagonist), BQ610 (an ETA antagonist), PD142893 (an ET(A/ …
Characterization of a transformed rat retinal ganglion cell line.
Krishnamoorthy RR, Agarwal P, Prasanna G, Vopat K, Lambert W, Sheedlo HJ, Pang IH, Shade D, Wordinger RJ, Yorio T, Clark AF, Agarwal N. Krishnamoorthy RR, et al. Among authors: prasanna g. Brain Res Mol Brain Res. 2001 Jan 31;86(1-2):1-12. doi: 10.1016/s0169-328x(00)00224-2. Brain Res Mol Brain Res. 2001. PMID: 11165366 Retracted.
One of the retinal cell clones, designated RGC-5, was positive for Thy-1, Brn-3C, Neuritin, NMDA receptor, GABA-B receptor, and synaptophysin expression and negative for GFAP, HPC-1, and 8A1, suggesting that it represented a putative RGC clone. ...
One of the retinal cell clones, designated RGC-5, was positive for Thy-1, Brn-3C, Neuritin, NMDA receptor, GABA-B receptor, and synap …
Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes.
Desai D, He S, Yorio T, Krishnamoorthy RR, Prasanna G. Desai D, et al. Among authors: prasanna g. Biochem Biophys Res Commun. 2004 Jun 4;318(3):642-8. doi: 10.1016/j.bbrc.2004.04.073. Biochem Biophys Res Commun. 2004. PMID: 15144886
Hypoxia enhanced TNF-alpha-mediated ET-1 synthesis and release (by 5-fold) and also significantly increased TNF-alpha- and ET-1-mediated hONA proliferation. PD142893 (1 microM), an ET(A/B) receptor antagonist, blocked ET-1-mediated hONA proliferation both under normoxia an …
Hypoxia enhanced TNF-alpha-mediated ET-1 synthesis and release (by 5-fold) and also significantly increased TNF-alpha- and ET-1-mediated hON …
Localization of endothelin-converting enzyme in bovine optic nerve and retina.
Dibas A, Prasanna G, Yorio T. Dibas A, et al. Among authors: prasanna g. J Ocul Pharmacol Ther. 2005 Aug;21(4):288-97. doi: 10.1089/jop.2005.21.288. J Ocul Pharmacol Ther. 2005. PMID: 16117692
Presently, ET-1 receptors and Big ET-1 converting activities were characterized in bovine optic nerve and the retina. The ET(B) receptor was detected in both the optic nerve and retina by immunoblotting and cross-linking, using 125I-ET-1. ...Western blotting revealed the p …
Presently, ET-1 receptors and Big ET-1 converting activities were characterized in bovine optic nerve and the retina. The ET(B) recep …
17 results